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Horseshoe Southern Indiana 11999 Casino Center Drive SE Elizabeth, IN 47117 Email Us Info: 1.866.676.SHOE Hotel Reservations: 1.866.766.2671 VIP Services: 1.877.367.3767 Convention and Hotel Sales: 1.877.462.7663 Directions to Horseshoe Southern Indiana Directions from Louisville: Horseshoe Casino Hotel is just 20 minutes from downtown Louisville. Take I-64 west across the Sherman Minton Bridge. Take the first exit, exit 123 New Albany. Go to the second stop light, turn right onto State St. Proceed straight 3 blocks to Main St and turn right. Main St will turn into Highway 111. Horseshoe will be approximately 8 miles down Highway 111. Directions from Indianapolis: From Indianapolis take I-65 toward Louisville. Take I-265 West, exit 6. Follow I-265 about 5 miles. I-265 ends at I-64. Take the East Bound ramp toward Louisville. Take the New Albany exit, number 123. You will see the Holiday Inn Express at the bottom of the ramp. Go straight 2 blocks to Main St. Turn Right. Main St. will turn into Highway 111. When the road splits follow it to the left and crossover the railroad tracks. Horseshoe is approximately 8 miles down Highway 111. Directions from Cincinnati: From the Cincinnati area take I-71 South to Louisville to I-64 West to St. Louis. Cross the Sherman Minton Bridge. Take the first exit, exit 123 New Albany. Go to the second stop light, turn right onto State St. Proceed straight 3 blocks to Main St and turn right. Main St will turn into Highway 111. Horseshoe will be approximately 8 miles down Highway 111. Directions from Lexington: From the Lexington area take 1-64 West through Louisville and cross the Sherman Minton Bridge. Take the first exit, exit 123 New Albany. Go to the second stop light, turn right onto State St. Proceed straight 3 blocks to Main St and turn right. Main St will turn into Highway 111. Horseshoe will be approximately 8 miles down Highway 111.
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